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Picture of D-a-tocopheryl polyethylene glycol succinate

D-a-tocopheryl polyethylene glycol succinate

Tocophersolan is a water-soluble amphipathic formulation of d-alpha-tocopherol succinate coupled, through a succinate linker, to polyethylene glycol (PEG) 1000.
SKU: 9002-96-4
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Tocophersolan is a water-soluble amphipathic formulation of d-alpha-tocopherol succinate coupled, through a succinate linker, to polyethylene glycol (PEG) 1000. Due to its amphipathic property in which it forms its own micelles, tocophersolan is easily taken up into enterocytes, even in the absence of bile salts; fat soluble d-alpha-tocopherol is then released after hydrolysis. This formulation enhances the absorption of d-alpha-tocopherol compared to the administration of free d-alpha-tocopherol. In addition, tocophersolan may enhance the absorption of water-insoluble agents and other fat-soluble vitamins.

Vitamin E supplement, antioxidant Tocofersolan (INN) or tocophersolan is a synthetic water-soluble version of vitamin E. Natural forms of vitamin E are fat soluble, but not water-soluble. Tocofersolan is polyethylene glycol derivative of -tocopherol that enables water solubility.

Products specifications
Attribute nameAttribute value
CAS NO9002-96-4
SynonymsVitamin E polyethylene glycol succinate, Vitamin E-TPGS, TPGS
FormulaC33H54O5(C2H4O)n
Molecular Weight550 g/mol
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