Apigenin

Apigenin (4′,5,7-trihydroxyflavone), found in many plants, is a natural product belonging to the flavone class that is the aglycone of several naturally occurring glycosides.
SKU: 520-36-5
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Apigenin (4′,5,7-trihydroxyflavone), found in many plants, is a natural product belonging to the flavone class that is the aglycone of several naturally occurring glycosides. It is a yellow crystalline solid that has been used to dye wool.In in vitro experiments and animal studies, a variety of potential biological activities of apigenin have been identified. Apigenin induces autophagy (a kind of cellular waste-recycling system) in leukemia cells, which may support a possible chemopreventive role. Induced autophagy interferes with the action of the chemotherapy drug vincristine. Apigenin is a potent inhibitor of CYP2C9,an enzyme responsible for the metabolism of many pharmaceutical drugs in the body. Apigenin dimers can reverse the highest level of drug resistance found in cancer stem cells. Apigenin is a plant-derived flavonoid that has significant promise as a skin cancer chemopreventive agent

Products specifications
Attribute nameAttribute value
CAS NO520-36-5
FormulaC15H10O5
Molecular Weight270.240 gmol−1
SynonymsSpigenin, Apigenol, Chamomile, 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-benzopyrone, 4′,5,7-Trihydroxyflavone
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